Commentary: Bridging anticoagulation for mechanical heart valves: Haven't we crossed this bridge before?
نویسندگان
چکیده
منابع مشابه
Anticoagulation for Mechanical Heart Valves
Although mechanical heart valves (MHV) are more durable than tissue valves, they are more thrombogenic. Consequently, patients with MHV require long-term anticoagulation with vitamin K antagonists, such as warfarin. Although effective, warfarin has well-known limitations, including multiple drug and food interactions, and the challenges of coagulation monitoring and maintaining the internationa...
متن کاملeComment: Anticoagulation for mechanical heart valves: a current assessment.
Table 1 Reported cases of well functioning mechanical valve without anticoagulation Reference Mean age n Type of Position Mean follow-up Treatment with Peak (years) valve (n) of valve period without anticoagulation gradient anticoagulation (months) across (years) valve thrombotic prophylaxis are from non-randomized case series without controls w2x. Uncomplicated functioning without anticoagulat...
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T he management of pregnant women with mechanical heart valves is challenging. Recently, based on small numbers of patients and poor-quality data, correspondence from Aventis Pharmaceuticals Inc has described treatment “failures” and concerns about teratogenicity with the use of the low-molecular-weight heparin (LMWH) enoxaparin. The company issued a “Warning” that enoxaparin should not be used...
متن کاملAnticoagulation in patients with mechanical heart valves: follow the guidelines!
year: the lowest in the youngest age group and the highest in the oldest. Intracranial haemorrhage was seen at an unacceptable rate (0.6–0.7/year) in all age groups. Therefore, the authors conclude that the use of mechanical AVR below the age of 60 years is associated with a similar rate of intracranial bleeding as seen in older patients. This report shows the deleterious effect of over-anticoa...
متن کامل"Bridging" and mechanical heart valves: perils, promises, and predictions.
Measurement of the prothrombin time, which is standardized by reporting the result as the international normalized ratio (INR), assesses the anticoagulant effect of warfarin. For most mechanical heart valves, the target INR ranges between 2.0 and 3.5. In the postoperative cardiac surgical setting, patients are usually started on low doses of warfarin because they tend to have impaired hepatic m...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2019
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2018.07.067